Characterization of an Extracellular Keratinase from Microsporum canis.

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Dermatophytosis, Microsporum canis, Trichophyton mentagrophytes, Microsporum gypseum

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Extracellular proteolytic activity and molecular analysis of Microsporum canis strains isolated from symptomatic and asymptomatic cats.

Microsporum canis is the main zoophylic dermatophyte in dogs and cats, and it is also an important zoonotic agent. The literature showed that cats are asymptomatic carriers of M. canis. This is apparently due to host resistance and/or the presence of strains with lower virulence. This study was aimed to evaluate the keratinolytic, elastinolytic and collagenolytic activities of M. canis strains ...

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Carbohydrate metabolism in Microsporum canis.

Enzyme systems concerned in the breakdown of carbohydrates by dennatophytes have been little studied, the principal contribution being a study of a number of enzymes of the glycolytic and hexosemonophosphate pathways and of the tricarboxylic acid cycle in cell-free extracts of Trichophyton mentagrophytes (Jensen, Altschuller & Bard, 1957). The effect of different substrates and pH values on the...

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Secreted metalloprotease gene family of Microsporum canis.

Keratinolytic proteases secreted by dermatophytes are likely to be virulence-related factors. Microsporum canis, the main agent of dermatophytosis in dogs and cats, causes a zoonosis that is frequently reported. Using Aspergillus fumigatus metalloprotease genomic sequence (MEP) as a probe, three genes (MEP1, MEP2, and MEP3) were isolated from an M. canis genomic library. They presented a quite-...

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ژورنال

عنوان ژورنال: Nippon Ishinkin Gakkai Zasshi

سال: 2000

ISSN: 0916-4804,1882-0476

DOI: 10.3314/jjmm.41.257